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Reimbursement Review

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Displaying 51 - 75 of 1426
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Title Brand Name Generic Name Files Therapeutic Area Recommendation Type Status Submission Date Recommendation Date Project Number
clindamycin plus benzoyl perox... Cabtreo clindamycin plus benzoyl peroxide and adapalene
Recommendation and Reason Patient and Clinician Group inputClinical and Pharmacoeconomic Combined ReportFeedback on Draft Recommendation
 acne vulgaris Reimburse with clinical criteria and/or conditions Complete SR0794-000
danicopan Voydeya danicopan
Recommendation and ReasonsPatient and Clinician Group InputClinical and Pharmacoeconomic Combined ReportFeedback on Draft Recommendation
 Paroxysmal nocturnal hemoglobinuria (PNH) Reimburse with clinical criteria and/or conditions Complete SR0815-000
elexacaftor/tezacaftor/ivacaft... Trikafta elexacaftor/tezacaftor/ivacaftor and ivacaftor
Recommendation and Reason Clinical and Pharmacoeconomic Combined ReportFeedback on Draft RecommendationPatient and Clinician Group input
 Cystic fibrosis, F508del or responsive CFTR mutation, 2 years and older Reimburse with clinical criteria and/or conditions Complete SR0837-000
burosumab Crysvita burosumab
Recommendation and Reason Patient and Clinician Group inputClinical and Pharmacoeconomic Combined ReportFeedback on Draft Recommendation
 Treatment of X-Linked Hypophosphatemia Reimburse with clinical criteria and/or conditions Complete SR0818-000
lebrikizumab Ebglyss lebrikizumab
Recommendation and Reason Clinical and Pharmacoeconomic Combined ReportFeedback on Draft RecommendationPatient and Clinician Group input
 atopic dermatitis Do not reimburse Complete SR0819-000
Prostate Cancer
Final Report
 Prostate Cancer Active PH0050-000
ivosidenib Tibsovo ivosidenib
Recommendation and Reason Patient and Clinician Group InputClinical and Pharmacoeconomic Combined ReportFeedback on Draft Recommendation
 Acute myeloid leukemia (AML) Reimburse with clinical criteria and/or conditions Complete PC0349-000
pembrolizumab Keytruda pembrolizumab
Recommendation and Reason Clinical and Pharmacoeconomic Combined ReportFeedback on Draft RecommendationPatient and Clinician Group Input
 Gastric or gastroesophageal junction (GEJ) adenocarcinoma Reimburse with clinical criteria and/or conditions Complete PC0356-000
abemaciclib Verzenio abemaciclib
Recommendation and Reason Patient and Clinician Group inputClinical and Pharmacoeconomic Combined ReportFeedback on Draft Recommendation
 Adjuvant treatment of HR-positive, HER2-negative early breast cancer Reimburse with clinical criteria and/or conditions Complete PC0345-000
osimertinib Tagrisso osimertinib
Recommendation and Reason Patient and Clinician Group InputClinical and Pharmacoeconomic Combined ReportFeedback on Draft Recommendation
 Non-small cell lung cancer Reimburse with clinical criteria and/or conditions Complete PC0336-000
baricitinib Olumiant baricitinib
Recommendation and ReasonsPatient and Clinician Group inputClinical and Pharmacoeconomic Combined ReportFeedback on Draft Recommendation
 Alopecia areata, severe Reimburse with clinical criteria and/or conditions Complete SR0843-000
secukinumab Cosentyx secukinumab
Recommendation and ReasonsPatient and Clinician Group inputClinical and Pharmacoeconomic Combined ReportFeedback on Draft Recommendation
 Hidradenitis suppurativa Reimburse with clinical criteria and/or conditions Complete SR0781-000
capivasertib Truqap capivasertib
Recommendation and ReasonsClinical and Pharmacoeconomic Combined ReportFeedback on Draft RecommendationPatient and Clinician Group Input
 HR-positive, HER2-negative locally advanced or metastatic breast cancer Reimburse with clinical criteria and/or conditions Complete PC0341-000
Brentuximab vedotin Adcetris Brentuximab vedotin
Recommendation and ReasonsClinical and Pharmacoeconomic Combined ReportFeedback on Draft RecommendationPatient and Clinician Group Input
 Hodgkin lymphoma Reimburse with clinical criteria and/or conditions Complete PC0371-000
remdesivir Veklury remdesivir
Recommendation and Reason Clinical and Pharmacoeconomic Combined ReportFeedback on Draft RecommendationPatient and Clinician Group Input
 COVID-19 in hospitalized patients Reimburse with clinical criteria and/or conditions Complete SR0833-000
remdesivir Veklury remdesivir
Recommendation and Reason Clinical and Pharmacoeconomic Combined ReportPatient and Clinician Group InputStakeholder feedback on Draft Recommendation
 COVID-19 in non-hospitalized patients Reimburse with clinical criteria and/or conditions Complete SR0834-000
inclisiran Leqvio inclisiran
Recommendation and ReasonsClinical and Pharmacoeconomic Combined ReportFeedback on Draft RecommendationPatient and Clinician Group Input
 Primary hypercholesterolemia Reimburse with clinical criteria and/or conditions Complete SR0791-000
cariprazine Vraylar cariprazine
Recommendation and Reason Clinical and Pharmacoeconomic Combined ReportFeedback on Draft RecommendationPatient and Clinician Group Input
 Schizophrenia Reimburse with clinical criteria and/or conditions Complete SR0827-000
etrasimod Velsipity etrasimod
Recommendation and Reason Patient and Clinician Group InputClinical and Pharmacoeconomic Combined ReportStakeholder feedback on Draft Recommendation
 Ulcerative colitis Reimburse with clinical criteria and/or conditions Complete SR0795-000
cabotegravir Apretude cabotegravir
Recommendation and Reason Patient and Clinician Group InputClinical and Pharmacoeconomic Combined ReportStakeholder feedback on Draft Recommendation
 HIV-1 infection, pre-exposure prophylaxis Reimburse with clinical criteria and/or conditions Complete SR0825-000
evolocumab Repatha evolocumab
Recommendation and Reason Clinical and Pharmacoeconomic Combined ReportFeedback on Draft RecommendationPatient and Clinician Group Input
 Primary hyperlipidemia Reimburse with clinical criteria and/or conditions Complete SR0821-000
Multiple Myeloma
Final Report
 Multiple Myeloma Complete PH0047-000
Large B cell lymphoma
Final Report
 Large B cell lymphoma Complete PH0048-000
Cutaneous Melanoma
Final Report
 Cutaneous Melanoma Complete PH0049-000
Pembrolizumab N/A Pembrolizumab
Recommendation and Reason Responses to Questions From the Drug ProgramsClinical and Pharmacoeconomic Combined ReportStakeholder Input
 Melanoma (Skin) Reimburse with clinical criteria and/or conditions Complete PX0346-000

Health Technology Review

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Displaying 51 - 75 of 602
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Title Description Files Last Updated Project Sub Line Status Project Number
Early Biologic Treatment for Inflammatory Bowel Disease
Early Biologic Treatment for Inflammatory Bowel Disease
Rapid Review Completed RC1552-000
The Utilization of PCSK9 Inhibitors in Familial Hypercholesterolemia
Technology Review Active HC0094-000
Airway Management in Out-of-Hospital Emergencies
Airway Management in Out-of-Hospital Emergencies
Rapid Review Completed RC1555-000
BRAF and MEK Inhibitors for Active or Symptomatic Melanoma Brain Metastasis
BRAF and MEK Inhibitors for Active or Symptomatic Melanoma Brain Metastasis
Rapid Review Completed RC1549-000
Re-treatment With Immune Checkpoint Inhibitors: Utilization Analysis
Technology Review In Progress HC0093-000
The Effectiveness of PCSK9 Inhibitors in Familial Hypercholesterolemia
Observational Study Active OS0011-000
Bilateral Opportunistic Salpingectomy to Reduce the Incidence of Ovarian Cancer
Bilateral Opportunistic Salpingectomy to Reduce the Incidence of Ovarian Cancer
 Summary with Critical Appraisal Completed RC1550-000
Lenvatinib for the Treatment of Hepatocellular Carcinoma After Liver Transplant
Lenvatinib for the Treatment of Hepatocellular Carcinoma After Liver Transplant
Rapid Review Completed RC1553-000
Cost-Effectiveness of Conjugate Pneumococcal Vaccines in At-Risk Adults Aged 18 to 64 Years
Cost-Effectiveness of Conjugate Pneumococcal Vaccines in At-Risk Adults Aged 18…
 Technology Review Completed HE0054-000
Short-Cycle Autoclave Sterilization of Instruments in Same-Day Ophthalmic Surgeries
Short-Cycle Autoclave Sterilization of Instruments in Same-Day Ophthalmic Surgeries
Rapid Review Completed RC1547-000
Continuously Diffused Therapy for Wound Healing To inform decisions about continuously diffused oxygen (CDO) therapy for wound healing, we identified and summarized literature comparing the clinical effectiveness and cost-effectiveness of CDO therapy versus conventional wound care.
Continuously Diffused Therapy for Wound Healing
Rapid Review Completed RC1548-000
Review of Guidelines on Second-Line Therapy for Patients With Relapsing-Remitting Multiple Sclerosis: A 2024 Update
Review of Guidelines on Second-Line Therapy for Patients With Relapsing-Remitting Multiple Sclerosis: A 2024 Update
Rapid Review Completed RC1541-000
Thrombopoietin Receptor Agonists as Second-Line Treatment in Children With Ongoing Immune Thrombocytopenia
Thrombopoietin Receptor Agonists as Second-Line Treatment in Children With Ongo…Protocol List of included studies
 Technology Review Completed HC0033-000
Methoxyflurane Inhalation as an Analgesic for Minor Gynecological, Ambulatory, or Emergency Procedures
Methoxyflurane Inhalation as an Analgesic for Minor Gynecological, Ambulatory, or Emergency Procedures
Rapid Review Completed RC1545-000
Retesting Intervals for Tryptase
Retesting Intervals for Tryptase
Rapid Review Completed RC1546-000
Drug Shortages and Patient Harms The objective of our report is to summarize the evidence on patient outcomes associated with supply chain disruptions of pharmaceuticals and vaccines.
Drug Shortages and Patient Harms
 Technology Review Completed HC0072-000
Safety of Ozempic for Type II Diabetes
Final ReportSummary Report
 Observational Study Completed OS0005-000
An Inventory of Rare Disease Registries in the Canadian Landscape
An Inventory Report of Rare Disease Registries in the Canadian Landscape
 Environmental Scan Completed CP0033-000
Review of Guidelines on Clonidine for Various Indications
Review of Guidelines on Clonidine for Various Indications
Rapid Review Completed RC1543-000
Efficacy and Safety of Treatment Options for Uncomplicated Gonococcal Infections
Efficacy and Safety of Treatment Options for Uncomplicated Gonococcal Infections
Summary Report
 Rapid Review with Expert Input Completed RD0070-000
The Canadian Medical Imaging Inventory: 2022–2023
Canadian Medical Imaging Inventory 2022– 2023: CTCanadian Medical Imaging Inventory 2022– 2023: MRICanadian Medical Imaging Inventory 2022– 2023: PET-CT and PET-MRICanadian Medical Imaging Inventory 2022–2023: SPECT and SPECT-CTCanadian Medical Imaging Inventory 2022–2023: Provincial and Territorial Overvi…Canadian Medical Imaging Inventory 2022–2023: The Medical Imaging TeamCanadian Medical Imaging Inventory 2022– 2023: MethodsThe Canadian Medical Imaging Inventory 2022–2023 - Evidence Preview
 Technology Review Completed HC0024-000
Evidence Review of Treatment Options for Uncomplicated Gonococcal Infections
Final ReportSummary Report
 Technology Review Completed RE0046-000
Re-Treatment With Immune Checkpoint Inhibitors
Final Report
 Summary with Critical Appraisal Completed RC1544-000
Drug Shortages in Canada
Final Report
 Environmental Scan Completed ES0381-000
Opioid Analgesics to Treat Chronic Noncancer Pain among Patients Prescribed Opioid Agonist Therapy or With Opioid Use Disorder Our systematic review examined 5 observational studies on the safety of opioid analgesics alone or with opioid agonist therapy for chronic pain in patients with opioid use disorder or a history of opioid use disorder.
Summary ReportFinal ReportSupplemental DocumentProject Protocol
 Systematic Review Completed RE0045-000

Horizon Scan

Last Updated
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Displaying 51 - 75 of 110
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Title Description Files Last Updated Project Sub Line Status Project Number
2022 Health Technology Trends to Watch
2022 Health Technology Trends to Watch
 Roundup Completed ER0012-000
Artificial Intelligence for the Prediction of Sepsis in Adults
Artificial Intelligence for the Prediction of Sepsis in Adults
 Health Technology Update Completed EN0034-000
Vacuum-Induced Uterine Tamponade for Postpartum Hemorrhage
Vacuum-Induced Uterine Tamponade for Postpartum Hemorrhage
Health Technology Update Active EN0035-000
Emerging Drugs for Amyotrophic Lateral Sclerosis
Emerging Drugs for Amyotrophic Lateral Sclerosis
 Emerging Health Technologies Completed EH0100-000
Emerging Drugs for Generalized Myasthenia Gravis
Horizon Scan
 Emerging Health Technologies Completed EH0099-000
An Overview of Smartphone Apps
Horizon Scan
 Emerging Health Technologies Completed EH0098-000
Renal Denervation for People with Hypertension
Health Technology Update
 Health Technology Update Completed EN0038-000
Self-Sampling Devices for HPV Testing
Horizon Scan
 Emerging Health Technologies Completed EH0101-000
An Overview of Emerging Point-of-Care Tests for Differentiating Bacterial and Viral Infections
An Overview of Emerging Point-of-Care Tests for Differentiating Bacterial and V…
 Emerging Health Technologies Completed EH0097-000
Adaptive Deep Brain Stimulation for the Treatment of Parkinson Disease and Essential Tremor
Adaptive Deep Brain Stimulation for the Treatment of Parkinson Disease and Esse…
 Health Technology Update Completed EN0036-000
Neuromodulation Technologies for the Treatment of Alzheimer Disease
Neuromodulation Technologies for the Treatment of Alzheimer Disease
 Emerging Health Technologies Completed EH0095-000
An Overview of Post‒COVID-19 Condition (Long COVID)
An Overview of Post‒COVID-19 Condition (Long COVID)
Emerging Health Technologies Completed EH0096-000
Pharyngeal Electrical Stimulation Device for the Treatment of Dysphagia Associated With Neurologic Conditions
Pharyngeal Electrical Stimulation Device for the Treatment of Dysphagia Associ…
 Health Technology Update Completed EN0030-000
Barricaid Spinal Implant Device
Horizon Scan Newsletter
 Health Technology Update Completed EN0032-000
Breath Tests for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2
Breath Tests for the Detection of Severe Acute Respiratory Syndrome Coronavirus…
 Health Technology Update Completed EN0039-000
Portable Neuromodulation Stimulator for chronic balance or gait impairment
Horizon Scan Newsletter
 Health Technology Update Completed EN0031-000
Combined Testing for Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza
Combined Testing for Severe Acute Respiratory Syndrome Coronavirus 2 and Influe…
 Health Technology Update Completed EN0029-000
Wearable Respiratory Sensor for the Detection of Opioid-Induced Respiratory Depression
EN0028 Respmeter Newsletter Final.pdf
Health Technology Update Completed EN0028-000
Direct to Patient Virtual Visits
An Overview of Direct-to-Patient Virtual Visits in Canada
 Emerging Health Technologies Completed EH0091-000
Framework for Drugs for Rare Diseases
es0355-drugs-for-rare-diseases-pw.pdf
Environmental Scan Completed ES0355-000
2021 Health Technology Trends to Watch
ER0011 Horizon Scanning 2021 Tech Trends v8.0.pdf
Roundup Completed ER0011-000
Rapid Point-of-Care Testing for COVID-19
Rapid Point-of-Care Testing for COVID-19
 Emerging Health Technologies Complete RB1536-000 - EH0093-000
Serological Tests for COVID-19
Serological Tests for COVID-19The Role of Different Types of Tests in the COVID-19 Pandemic
 Emerging Health Technologies Completed EH0085-000
Connected Devices to Support Remote Examination and Diagnosis in Primary Care and Specialty Care
Emerging Health Technologies Completed EH0088-000
COVID-19 Testing: A Summary of Testing Methods
COVID-19 Testing: A Summary of Testing Methods
 Emerging Health Technologies Completed EH0090-000

Projects in Progress

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Title Description Files Last Updated Project Line Project Sub Line Status Project Number
mirikizumab
Patient and Clinician Group input
 Reimbursement Review Active SR0880-000
rozanolixizumab
Draft RecommendationPatient and Clinician Group Input
 Reimbursement Review Active SR0846-000
ruxolitinib
Draft RecommendationPatient and Clinician Group input
 Reimbursement Review Active SR0835-000
abemaciclib
Patient and Clinician Group input
 Reimbursement Review Active PC0409-000
abemaciclib
Patient and Clinician Group input
 Reimbursement Review Active PC0400-000
efanesoctocog alfa
Draft RecommendationPatient and Clinician Group Input
 Reimbursement Review Active ST0840-000
guselkumab
Patient and Clinician Group Input
 Reimbursement Review Active SR0882-000
dupilumab
Patient and Clinician Group input
 Reimbursement Review Active SR0878-000
delgocitinib
Patient and Clinician Group input
 Reimbursement Review Received SR0875-000
omaveloxolone
Draft Recommendation Patient and Clinician Group input
 Reimbursement Review Active SR0864-000
daridorexant
Patient and Clinician Group input
 Reimbursement Review Active SR0862-000
amivantamab
Patient and Clinician Group input
 Reimbursement Review Active PC0393-000
lazertinib and amivantamab
Patient and Clinician Group input
 Reimbursement Review Active PC0392-000
inavolisib
Patient and Clinician Group Input
 Reimbursement Review Active PC0382-000
pembrolizumab
Recommendation and ReasonsPatient and Clinician Group input
 Reimbursement Review Active PC0369-000
quizartinib
Patient and Clinician Group Input
 Reimbursement Review Active PC0359-000
venetoclax
Patient and Clinician Group Input
 Reimbursement Review Active PC0402-00
teplizumab
Patient and Clinician Group input
 Reimbursement Review Active SR0867-000
osimertinib
Patient and Clinician Group input
 Reimbursement Review Active PC0398-000
polatuzumab vedotin
Patient and Clinician Group Input
 Reimbursement Review Active PC0397-000
pembrolizumab
Patient and Clinician Group Input
 Reimbursement Review Active PC0387-000
talquetamab
Recommendation and ReasonsPatient and Clinician Group Input
 Reimbursement Review Active PC0363-000
ribociclib
Patient and Clinician Group input
 Reimbursement Review Active PC0395-000
setmelanotide
Reimbursement Review Not filed NS0041-000
empagliflozin
Reimbursement Review Not filed NS0040-000

Provisional Funding Algorithm

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Title Tumour Type Therapeutic Area Files Project Number Project Status Final Recommendation/Report
RET fusion-positive non-small ... Lung RET fusion-positive non-small cell lung cancer
Final Report
 PH0026-000 Complete
Non-Small Cell Lung Cancer (NS... Lung Non-Small Cell Lung Cancer (NSCLC) with Activating Epidermal Growth Factor Receptor (EGFR) Mutations
Final Report
 PH0028-000 Complete
NSCLC without actionable oncog... Lung Unmutated Non-small cell lung cancer
Final Report
 PH0012-000 Complete
RET fusion-positive non-small ... Lung RET fusion-positive non-small cell lung cancer
PH0020-000 Withdrawn
NSCLC without actionable oncog... Lung Non-Small Cell Lung Cancer
Final Report
 PH0015-000 Completed
NSCLC without actionable oncog... Lung Non-small Cell Lung Cancer
PH0059-000 Merged
Non-small-cell lung cancer Lung Non-small-cell lung cancer
Proposed ScopeProposed Scope # PH0059-000
PH0065-000 Active
Non-small-cell lung cancer (NS... Lung Non-Small Cell Lung Cancer (NSCLC) with Activating Epidermal Growth Factor Receptor (EGFR) Mutations
Final Report
 PH0071-000 Complete
Large B cell lymphoma Lymphoma Large B cell lymphoma
Final Report
 PH0040-000 Complete
Adult Classical Hodgkin Lympho... Lymphoma Adult Classical Hodgkin Lymphoma
Final Report
PH0052-000 Complete
Large B cell lymphoma Lymphoma Large B cell lymphoma
Final Report
 PH0048-000 Complete
Large B-Cell Lymphoma Lymphoma Large B-Cell Lymphoma
Final Report
 PH0027-000 Completed
Adult Classical Hodgkin Lympho... Lymphoma Adult Classical Hodgkin Lymphoma
Final Report
 PH0007-000 Complete
Hodgkin lymphoma Lymphoma Hodgkin lymphoma
Proposed Scope
 PH0079-000 Open for Input
Mantle cell lymphoma Lymphoma Mantle cell lymphoma
Proposed Scope
PH0087-000 Active
Diffuse large B cell lymphoma ... Lymphoma Diffuse large B
Proposed Scope
 PH0078-000 Open for Input
Multiple Myeloma Myeloma Multiple Myeloma
Proposed Scope
PH0086-000 Open for Input
Multiple Myeloma Myeloma Multiple Myeloma
Final Report
 PH0047-000 Complete
Multiple Myeloma Myeloma Multiple myeloma
Final Report
 PH0031-000 Complete
Multiple myeloma Myeloma Multiple myeloma
Multiple myeloma - Final Report
 PH0011-000 Complete
Multiple Myeloma Myeloma Multiple Myeloma
PH0060-000 Merged
Multiple Myeloma Myeloma Multiple Myeloma
Draft ReportScoping Document
 PH0068-000 Active
Multiple myeloma Myeloma Multiple myeloma
Scoping DocumentProposed Project Scope for PH0060-000
 PH0074-000 Open for Input
Multiple Myeloma (MM) Myeloma Multiple Myeloma (MM)
Multiple Myeloma (MM) - Final Report
 PH0014-000 Complete
Differentiated Thyroid Carcino... Other Differentiated Thyroid Carcinoma
Final Report
 PH0021-000 Complete