naloxegol

Details

Key Milestones2
Submission receivedNovember 22, 2024
Expert committee meeting (initial)May 15, 2025
Draft recommendation posted for stakeholder feedbackJune 02, 2025
End of feedback periodJune 16, 2025
Final recommendation postedJuly 17, 2025
CDA-AMC review report(s) postedJuly 30, 2025

nivolumab

Details

Key Milestones2
Submission receivedNovember 27, 2024
Expert committee meeting (initial)May 15, 2025
Draft recommendation posted for stakeholder feedbackJune 05, 2025
End of feedback periodJune 19, 2025
Clarification:

- Reconsideration: minor revisions requested by drug programs

- Request for reconsideration accepted

CDA-AMC review report(s) postedAugust 05, 2025

fidaxomicin

Details

Key Milestones2
Submission receivedNovember 22, 2024
Expert committee meeting (initial)May 15, 2025
Draft recommendation posted for stakeholder feedbackJune 05, 2025
End of feedback periodJune 19, 2025
Final recommendation postedJuly 28, 2025
CDA-AMC review report(s) postedJuly 28, 2025

nemolizumab

Details

Key Milestones2
Call for patient/clinician input open21-Nov-24
Call for patient/clinician input closed17-Jan-25
Submission received07-Jan-25
Submission accepted21-Jan-25
Review initiated22-Jan-25
Draft CADTH review report(s) provided to sponsor for comment09-Apr-25
Deadline for sponsors comments22-Apr-25
CDA-AMC review report(s) and responses to comments provided to sponsor15-May-25
Expert committee meeting (initial)28-May-25
Clarification:

CDEC recommendation held pending receipt of NOC and evaluation of the finalized submission requirements

Draft recommendation issued to sponsor-
Draft recommendation posted for stakeholder feedback-
End of feedback period-

fecal microbiota

Details

Key Milestones2
Call for patient/clinician input open15-Nov-24
Call for patient/clinician input closed17-Jan-25
Submission received03-Jan-25
Submission accepted17-Jan-25
Review initiated20-Jan-25
Draft CADTH review report(s) provided to sponsor for comment11-Apr-25
Deadline for sponsors comments24-Apr-25
CDA-AMC review report(s) and responses to comments provided to sponsor15-May-25
Expert committee meeting (initial)28-May-25
Draft recommendation issued to sponsor11-Jun-25
Draft recommendation posted for stakeholder feedback19-Jun-25
End of feedback period04-Jul-25
Clarification:

- Reconsideration: major revisions requested by sponsor

Target CDEC reconsideration meeting date to be determined

dupilumab

Details

Key Milestones2
Call for patient/clinician input openNovember 12, 2024
Call for patient/clinician input closedJanuary 10, 2025
Submission receivedDecember 20, 2024
Submission acceptedJanuary 13, 2025
Review initiatedJanuary 14, 2025
Draft CADTH review report(s) provided to sponsor for commentApril 09, 2025
Deadline for sponsors commentsApril 22, 2025
CDA-AMC review report(s) and responses to comments provided to sponsorMay 15, 2025
Expert committee meeting (initial)May 28, 2025
Draft recommendation issued to sponsorJune 11, 2025
Draft recommendation posted for stakeholder feedbackJune 19, 2025
End of feedback periodJuly 04, 2025
Final recommendation issued to sponsor and drug plansJuly 17, 2025
Final recommendation postedAugust 05, 2025
Deadline for sponsor to submit redaction requests on draft CADTH review report(s)July 31, 2025
CDA-AMC review report(s) posted-

ribociclib

Details

Key Milestones2
Call for patient/clinician input openNovember 07, 2024
Call for patient/clinician input closedJanuary 06, 2025
Submission receivedDecember 19, 2024
Submission acceptedJanuary 13, 2025
Clarification:

- Submission was not accepted for review on 10 January 2025

Review initiatedJanuary 14, 2025
Clarification:

- Submission temporarily suspended

- Additional information has been received and the temporary suspension of the review has been lifted

Draft CADTH review report(s) provided to sponsor for commentApril 28, 2025
Deadline for sponsors commentsMay 07, 2025
CDA-AMC review report(s) and responses to comments provided to sponsorMay 30, 2025
Expert committee meeting (initial)June 11, 2025
Draft recommendation issued to sponsorJune 23, 2025
To
June 25, 2025
Draft recommendation posted for stakeholder feedbackJuly 03, 2025
End of feedback periodJuly 17, 2025

dupilumab

Details

Key Milestones2
Call for patient/clinician input openNovember 07, 2024
Call for patient/clinician input closedJanuary 06, 2025
Submission receivedDecember 18, 2024
Submission acceptedJanuary 09, 2025
Review initiatedJanuary 10, 2025
Draft CADTH review report(s) provided to sponsor for commentApril 08, 2025
Deadline for sponsors commentsApril 17, 2025
CDA-AMC review report(s) and responses to comments provided to sponsorMay 15, 2025
Expert committee meeting (initial)May 28, 2025
Draft recommendation issued to sponsorJune 10, 2025
Draft recommendation posted for stakeholder feedbackJune 19, 2025
End of feedback periodJuly 04, 2025
Final recommendation issued to sponsor and drug plansJuly 18, 2025
Final recommendation posted-
Deadline for sponsor to submit redaction requests on draft CADTH review report(s)August 01, 2025
CDA-AMC review report(s) posted-

Pharmaceutical Reviews Update — Issue 52

Details

Program Updates 

1. Updates to the Pharmacoeconomic Submission Process and Submission Requirements 

Making Our Economic Model Change Logs More Transparent to Our Partners 

Transparency is essential in economic modelling to make complex analyses more understandable, reliable, and actionable. We are taking a new step to increase the transparency around how we handle economic models that are submitted by a drug sponsor as part of a drug reimbursement review.