Eating disorders are serious but treatable conditions with the highest mortality rates among mental health disorders, accounting for approximately 10% to 15% of mental illness deaths. According to a Canadian Institute for Health Information (CIHI) report, hospitalizations for young females with eating disorders increased by more than 50% during the COVID-19 pandemic.
Emergency departments (EDs) across Canada are under strain and experiencing overcrowding, a situation in which the demand for health services in the ED exceeds the capacity of the ED, hospital, or community to deliver quality care in a reasonable amount of time. Recent evidence suggests that ED overcrowding is worsening in jurisdictions across Canada. This is in addition to an increasing trend of unexpected temporary ED closures and reductions of services across the country.
This Environmental Scan will assess the current regulations and policies that exist in Canada for governing pediatric medicines and formulations.
Projects listed as “in progress” are at various stages and points of completion. These products have different processes and timelines; therefore, the timing of posting of the final reports varies and expected completion dates may change. Find out more about Projects in Progress.
Automatic stop orders may reduce or have no significant effect on opioid-based prescriptions at the institutional level.
We did not find any evidence regarding a range of clinical outcomes (e.g., rates of opioid dependence, misuse, and diversion; reduction in opioid dependence, health-related quality of life, and adverse events) associated with automatic stop orders.
We did not find any evidence-based guidelines regarding the use of automatic stop orders for opioid prescriptions.
Given the limited number and observational, nonrandomized design of the included studies, as well as the absence of any evidence-based guidelines regarding the use of automatic stop orders for opioid prescriptions, it was difficult to draw any firm conclusions about the clinical effectiveness of automatic stop orders for opioid prescriptions in the Canadian context.
One relevant systematic review of high methodological quality did not include any randomized controlled trials (RCTs) on the effectiveness of nabilone for the treatment of posttraumatic stress disorder (PTSD).
We did not find any evidence-based guidelines on the use of nabilone for adults with PTSD.
The absolute risk of HIV transmission through sexual activity, reported as incidence rates of observed seroconversions across person-years of follow-up, ranged widely across the included studies of sex partners living with HIV with variable (or unreported) viral loads.
Two studies included sex partners living with HIV with suppressed viral loads of fewer than 200 copies/mL, reporting no phylogenetically linked seroconversions in either study.
This report summarizes information collected through a survey on the strategies used across Canada to conserve ICM supplies during the shortage, including:multidispensing practices used in medical imaging and pharmacy departments to conserve ICM supplydilution practices in medical imaging departments used to extend ICM supplychanges in ICM volumes used before and after the shortagethe adoption of other ICM conservation strategies (including weight-based dosing or using alternative imaging modalities).The report also explores the survey respondents’ perceived impact of reducing ICM volumes o
In recent years, the volume and variety of health-related data have increased exponentially; however, integrating evidence to inform decisions about the safety and effective of use of drugs depends on having timely access to fit for purpose data.